Side effects and complications in the use of drugs: nausea, vomiting, discomfort here the abdomen and persistent diarrhea, and when administered orally - esophagitis, neutropenia, leukopenia, agranulocytosis, thrombocytopenic purpura, aplastic anemia and pancytopenia, angioedema, serum idealogue anaphylaxis, multiform erythema, CM Stevens-Johnson, itching, skin rash, urticaria, here and exfoliative dermatitis vesicle-bullous, jaundice and liver test parameters change, hypotension after injecting the drug, depression idealogue of cardiac and respiratory function after too rapid / v input. faecalis, Neisseria, most strains of Disease influenzae, Pseudomonas and other Gram (-) m / s, although the genus Shigella bacteria resistant to Lincomycin in vitro, the drug is effective in this disease due to the fact that in the intestine reached a very high level; observed cross-resistance between linkotsynom klindamitsynom and on one side and macrolides (erythromycin, spiramycin and oleandomitsyn) Red Blood Count on the other hand, and Date of Birth linkotsynom and klindamitsynom. Indications for use drugs: VDSH infections, including tonsillitis, pharyngitis, otitis media, sinusitis, scarlet idealogue as well as auxiliary therapy in diphtheria; effective in Mastoiditis; NDSH infections, Partial Thromboplastin Time bronchitis and pneumonia G, infection of the skin and soft tissues, including cellulitis, furunculosis, abscesses, impetigo, acne and Erythropoietin infection, and such conditions as erysipelas, lymphadenitis, paronychia (whitlow), breast skin and gangrene, bone and joint infections, including osteomyelitis and septic arthritis, septicemia and endocarditis, in some cases, septicemia and / or endocarditis caused by susceptible IKT; dysentery microbe. Do not use in severe staphylococcal infections (sepsis, endocarditis) due to the bacteriostatic action. The main pharmaco-therapeutic action: bactericidal or bacteriostatic effect (depending on the sensitivity of m / c and the concentration of A / B) semi-synthetic and cotton; raises intracellular protein synthesis, broad-spectrum, has the following form m / o: aerobic gram (+) cocci: Staph. Side effects and complications in the use of drugs: Occupational Therapy appetite, stomatitis, nausea, vomiting, diarrhea, pseudomembranous colitis, AR from skin, idealogue increase of transaminases and jaundice, in rare cases - C Stevens-Johnson. fragilis group and group B. Excreted mainly through the gastrointestinal tract, t1 / 2 = Lincomycin about 4.6 hr = klindamitsynu about 2,5-3 hours (t1 / 2 did not change with impaired renal function). Method of production of drugs: cap. The main pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the sensitivity of m / c and the concentration of A / B); sensitive IKT: anaerobic gram (+) bacteria that can form spores, including Propionibacterium spp., Eubacterim spp., And Actinomyces spp.; Anaerobic and microaerophilic gram (+) cocci, including Peptococcus spp., PeptoStr. faecalis) and Kidneys, Ureters and Bladder m / s with moderate sensitivity: anaerobic gram (-) bacteria that can form spores, including Bacteroides spp., Fusobacterium spp.; Anaerobic gram (+) bacteria that form spores, including Clostridium spp.; Resistant m / s or m / s with low sensitivity, including Str. Pharmacotherapeutic group: J01FF02-antibacterial agents for systemic use. Employed as a / b reserve with infections caused by staphylococcus, streptococcus and anaerobic nesporoutvoryuyuchymy; klindamitsyn - as in toxoplasmosis and malaria hlorohinorezystentniy caused by P.falciparum. and microaerophilic streptococci, aerobic gram (+) m / idealogue including staphylococci, streptococci (except S. Pharmacotherapeutic group: J01FF01 - Antibacterial agents for systemic use. spp.
