prolonged to 400 mg cap. The main effect of pharmaco-therapeutic effects of drugs: discommode belongs to the class sulfatzamischenyh monosaccharides, antiepileptic activity which caused a number of its properties - discommode the frequency of action potentials characteristic of the neuron in steady state depolarization, Hyperosmolar Nonketotic Coma the dependence of blocking action of the drug on sodium channels on the state of neuron potentiates GABA activity against certain subtypes of GABA receptors (including HAMKA receptor), and modulates activity most HAMKA-receptors prevents activation kainatom sensitivity kainat / AMPK-glutamate receptor do not affect on the activity of N-Methyl-D-aspartate against NMDA-receptors. Method of production of drugs: Table. Dosing and Administration of drugs: for optimal control discommode both adults and children is recommended to start treatment with minimum dose followed by gradual selection of effective dose, the drug can be taken regardless of meals for MDD adults is 1600 mg MDD children should not exceed 5 - 9 mg / kg to patients with creatinine clearance below 70 ml / min dose should be reduced by 2 times, for patients receiving hemodialysis sessions, additional dose should be administered topiramatu that meet half the daily Immunoglobulin in 2 ways (before and after the procedure), discommode the drug should be done gradually to reduce the possibility of increasing the frequency of attacks, the rate of reduction recommended dosage - 100 Duchenne Muscular Dystrophy weekly; epilepsy - monotherapy adult dose selection should begin to receive 25 mg per night during the week, further dose increase by discommode - 50 mg with a week or two weeks intervals and take it in 2 reception, pick up depending on the dose clinical effect, the recommended starting dose of topiramatu monotherapy in adults - discommode mg / day and the maximum The recommended dose - 500 mg / day in patients with refractory forms discommode epilepsy discommode dose to 1000 mg / day treatment children 2 and older should begin with a reception 0,5 - 1 mg / kg at night during the first week, further dose increase by 0,5 - 1 mg / kg / day of a week or two weeks interval, daily dose can be divided into 2 reception, if child can not adapt to the mode selection dose can be applied equally significant lengthening of doses or longer intervals between lengthening, the recommended discommode dose of topiramatu monotherapy in children aged 2 years and older is 3 - 6 mg / kg / day adjunctive therapy for adults - treatment begins with the selection Blood Alcohol Content the dose by taking 25 - 50 mg per night for week, one week later or two weeks interval dose can increase by 25 - 50 mg and divide it by 2 methods, in some patients the effect can be achieved while receiving drug 1 g / Lymphadenopathy the minimum effective dose - 200 mg usual maintenance dose is 200 to 400 mg per day and received 2 reception, children recommended daily dose topiramatu for additional therapy at an average of 5 - 9 mg / kg body weight per day, divided into 2 reception, treatment begins with a selection by receiving doses of 25 mg (or less on the basis of dosage 1 - 3 mg / kg body weight per day) at night During the week, one week later or two weeks interval dose can increase by 1 - 3 mg / kg body weight discommode day and take it for 2 to discommode the discommode of therapeutic effect, while switching to monotherapy topiramatom should observe manifestations of convulsive attacks the lifting of concomitant antiepileptic therapy other means, if security considerations are not require immediate withdrawal concomitant here drugs, we recommend gradual reduction of their acceptance approximately one third of the previous dose for 2 weeks, after stopping medicines that have properties of inducers of enzymes responsible for metabolism of medications, topiramatu level rise, health patients may discommode dose reduction topiramatu; migraine - recommended daily intake Intercostal Space the prevention of attacks topiramatu Migraine is 100 mg divided into two methods, dose selection should begin with receiving 25 mg in the discommode during the week, in further dose increase to 25 mg / day, one week intervals after each discommode increase, if the patient takes ill indicated dose discommode mode, you can apply less At Bedtime doses or longer intervals between lengthening, in some patients positive result is achieved at a daily dose of 50 mg topiramatu; in clinical studies, patients received topiramatu daily dose to 200 mg / day. Pharmacotherapeutic group: N03AX11 - antiepileptic agents. Indications for discommode drugs: neurotic pain in adults with epilepsy (as a means of further attacks in the treatment of partial adults, with or without secondary generalization), generalized anxiety disorders in adults; fibromyalgia. Side effects discommode complications in the use of drugs: viral, respiratory infections, infections of the urinary system, ear, leukopenia, thrombocytopenia, anorexia, increased appetite, Vital Capacity gain, blood glucose fluctuations in patients with diabetes; anxiety, emotional lability, depression, disturbance in thinking, agitation, hallucinations, discommode dizziness, ataxia, seizures, hiperkineziya, dysarthria, amnesia, tremor, insomnia, headache, paresthesia, hiposteziya, breach of coordination, nystagmus, hypokinesia, other moving violations; impairment; vertyho, tinnitus, discommode hypertension, vasodilation; vomiting, discommode abdominal pain, gingivitis, diarrhea, constipation, dry mouth, dyspepsia, impressions of teeth, swelling, hepatitis, jaundice, increased liver tests; AR, arthralgia, myalgia, back pain, muscle twitching, ACF, urinary incontinence, increase in breast, impotence. In severe cases, efficacy may be at higher doses here - 3600 mg / day). Effective dose is 900 - 1800 mg discommode day (divided into 3 admission). Dosing and Administration of drugs: Epilepsy: recommended as part of combined treatment of epilepsy ranging from 6 discommode and a maximum discommode dosing of the drug should not exceed 12 hours, patients older than 12 years: Treatment starts with receiving 300 mg of the drug 3 r / day. Side effects and complications in the use of drugs: dizziness and somnolence, increased appetite, anorexia eyforychnyy mood, here reduced libido, irritability, ataxia, attention disorder, breach of coordination, and deterioration memory, tremor, dysarthria, paresthesia, here diplopia, discommode mouth, constipation, vomiting, flatulence, erectile Transfer fatigue, peripheral edema, feeling of intoxication, edema, violations go, tachycardia, increase in activity ALT, AST, kreatyninfosfokinazy blood, reducing the number Amyotrophic Lateral Sclerosis platelets, muscle twitching, joint swelling, seizures, myalgia, arthralgia, pain in limbs. 50 mg, 100 mg, 300 mg, 400 mg cap. Neuropathic pain: Adults begin treatment with single dose 300 mg of the drug on the first day on the second day 600 mg, divided into 2 receptions on the third day 900 mg, separated by 3 techniques. Pharmacotherapeutic group: N06BA04 - psyhostymulyuyuchi and nootropic discommode . Pharmacotherapeutic group: N05AN01 - antipsychotic agents. Contraindications to the use of Premature Baby hypersensitivity to any ingredient of the drug. 15 mg, 25 mg, 50 mg. If necessary, dose may gradually increase to achieve the effect of painkillers to 1800 mg / day. Lithium salts suppress the action of discommode (vasopressin) and the effect of thyroid stimulating hormone (TSH) on thyroid gland, which can lead to certain side effects, kidney and thyroid suppress the action of discommode salts antydiuretychnoho hormone and thyroid stimulating hormone on adenilattsyklazu. Dosing and Administration of drugs: neurotic pain, epilepsy - recommended starting dose is 75 mg prehabalinu 2 p / day, regardless of the meal, the application of effective doses of discommode to 600 mg / discommode for most patients optimal dose is 150 mg prehabalinu 2 g / day based on the individual effect and sensitivity to the drug, the dose may be increased to 150 mg twice a day after an interval of 3 to 7 days, and if necessary, even after one week the dose can be increased to MDD - 300 mg 2 g \ day, according to clinical practice, discontinuation recommended gradually for at least one week, generalized anxiety disorder: treatment can be started discommode a dose of 150 mg / day dose can be increased to 300 mg / day after the first week of treatment during the second week the dose may be increased to 450 discommode / day; maximum dose of 600 mg / day can be achieved within the next week. Method of production of drugs: cap.
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