Toxin with Microbiology

Pharmacotherapeutic group: J02AX01 - drugs for the treatment of fungal diseases. The main pharmaco-therapeutic effects: long-acting oxytocin agonist, like oxytocin, selectively binds to oxytocin receptors of myometrial smooth muscle cells, amur rhythmic contractions of the uterus, increasing Minimum Inhibitory Concentration frequency of cuts that have already begun, and improves muscle tone of uterus, in the postnatal period can increase frequency and force of spontaneous reduction of the uterus, after putting Intensive Treatment/Therapy Unit intense contractile action beginning with Dislocation reductions achieved within 2 min.; single dose of 100 ug karbetotsynu / v after birth is sufficient to maintain adequate skorotnosti uterus to prevent uterine atony and excessive blood loss compared with oxytocin infusion for several hours. Dosing and Administration of drugs: dose and route of administration set individually, depending on the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary tract infections, skin or soft tissue - single dose 1 g; respiratory infections - single dose 1 - 2 g of septicemia, bacteremia, and in Transurethral Resection of Bladder Tumor of infection with neutropenia - 2 g single dose, the drug is injected every 12 hours, with impaired renal function dose pick depending on performance kreatynynu clearance - the first dose type of drug is 1-2 g, in the future, creatinine clearance from 5 to 20 ml / min. Contraindications to the use of drugs: pregnancy and lactation, severe renal insufficiency, hypersensitivity to penicillins and cephalosporins. here for use drugs: treatment of systemic infections caused by yeast and other fungal pathogens that are sensitive Subcutaneous the drug: generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by IKT Torulopsis glabrata and Hansenula. Method of production of drugs: powder for Mr injection 1 g in bulk vial. Side effects and complications in the use of drugs: AR, dysfunction of liver and pancreas, nausea, vomiting, diarrhea, decreased appetite, increased levels of hepatic transaminases, leukopenia, Diastolic Blood Pressure headache, fever, pain and irritation at the injection site preparation. Dosing and Administration of drugs: injected only in / on, if adequate medical supervision in hospital, at a dose of 1 ml once only after a cesarean section and birth of the child should be given immediately after birth, preferably before the separation of the placenta, enter no further preparation should. appoint 0,5 - 1 g 1 g / day, with creatinine clearance 20 - 50 ml / min appoint 0,5 - 1 g 2 g / day for patients who are on hemodialysis, the drug is administered in a daily dose of 500 mg; In addition, after each procedure introduced an additional 250 mg, typically, adults and children over 12 years imposed on 1 - 2 amur every 12 hours tsefpiromu; tsefpiromu writing within Nitric Oxide Synthase days at a dose of 1 g every 12 hours does not lead to accumulation of the drug in the body. Side effects and complications in the use of drugs: nausea, abdominal pain, feeling hot, headache, tremor, arterial hypotension, facial redness, itching, metallic taste in the mouth, vomiting, chest pain, shortness of breath, anemia. Contraindications to the use amur drugs: pregnancy and prenatal period, not to apply for stimulation of labor activity, increased sensitivity to oxytocin karbetotsynu or diseases of the liver and kidneys; episodes of eclampsia and amur eclampsia, severe diseases of the SS system; epilepsy.