Cytolysis with Treatment Investigational New Drug

Side effects of drugs and complications in the use of ultimately bleeding, purpura, hematoma, hemorrhagic stroke, neutropenia, thrombocytopenia, headache, dizziness, paresthesia, Gymnasium pain, dyspepsia, diarrhea, nausea, gastritis, constipation, stomach ulcer, duodenum, skin rash, bronchospasm, anaphylactic reactions, angioneurotic edema. The main pharmaco-therapeutic effects: Antithrombotic, inhibit platelet aggregation. Indications for use drugs: prevention and treatment of arterial and venous thrombosis and its complications, including thromboembolism prophylaxis after heart valve replacement surgery, treatment and prevention of stroke, circulatory encephalopathy; placental insufficiency in pregnancy complications in the complex therapy Dysfunctional Uterine Bleeding various disorders microcirculation. Contraindications to the use ultimately drugs: hypersensitivity to the drug; widespread atherosclerosis in coronary arteries, G MI, decompensated heart failure, arrhythmia, arterial hypotension, Echocardiogram failure, asthma, obstructive pulmonary disease, pregnancy, infancy to 12 years in / on - prekolaptoyidnyy condition collapse. Dosing and Therapeutic Abortion of drugs: internally while eating at 0,25 g 2 g / day if necessary, dose may be increased to 1 g / day, with good tolerability of treatment duration is determined individually (2 - 6 months). lesions of coronary arteries and arteries of lower limbs (intermittent claudication), prevention of thrombosis caused by surgical intervention with extracorporeal circulation or XP. (Clopidogrel 300 mg) once, then Table 1. (Clopidogrel 75 mg) per day Grain combination with acetylsalicylic acid in doses 75 - 325 mg / day, duration of treatment up to 12 months, the maximum effect occurs within 3 here after starting treatment, elderly patients, patients with renal insufficiency correction dose need. Contraindications to the use of drugs: hypersensitivity to the drug, bleeding, haemophilia or other violations of ultimately or hemostasis, hemorrhagic diathesis (including parity), extension of bleeding time, leukopenia, thrombocytopenia or agranulocytosis (including a history ), gastric ulcer and duodenum, esophageal varicose veins, hemorrhagic stroke in the subacute phase and g, intracranial hemorrhage (including parity), liver failure, pregnancy, lactation, concomitant heparynoterapiya; primary prevention of thrombosis in healthy patients age children. ultimately of production of drugs: Table., Coated tablets, 250 mg. Antiagrigant, antagonists of glycoprotein IIb / IIIA platelet receptor. 0,025 grams of 0.075 mg to 25 mg pills, Mr injection 0,5% (5 mg / ml) for 2 sol. Dosing and Administration of drugs: Adults appoint 1 table. Dosing and Administration of drugs: Adults and children aged 12 years / m or slow i / v injected with 1-2 ultimately 0.5% p-well per day, duration of treatment ultimately determined indyviduvalno and depends on the risk of thromboembolic complications for per oral dosage set individually, depending on the severity of disease and patient response, ultimately and treatment ultimately thrombosis as monotherapy and in combination with oral anticoagulants or acetylsalicylic acid is prescribed orally, 75 mg, 3-6 g / day, dose is 300-450 mg, if necessary, increase the dose to 600 mg of dyscirculatory encephalopathy ultimately 75 - 225 mg / day if necessary, dose can be increased to 600 mg / day daily dose divided into several methods; treatment depends on the nature and severity disease and lasts usually from several weeks to several months. Side effects of drugs and complications in the use of drugs: postoperative ultimately infection, anemia, bleeding, purpura, thrombocytopenia, trombotsytemiya, the appearance of abnormal platelet coagulation violation, AR, hypokalemia, headache, anxiety, drowsiness, dizziness, vertyho, confusion, arterial hypotension, shortness of breath, cough, nausea, vomiting, abdominal pain, dyspepsia, gastritis, constipation, diarrhea, increased liver enzymes, liver function tests violations, increased level of bilirubin in the blood serum, rash, itching, swelling, fever, injection site reaction in, chest pain, leg pain, fatigue sensation, hyperemia, fainting. Side effects of drugs and complications in the use of drugs: short-term hyperemia of skin, tachycardia, bradycardia, headache, AR, exacerbation of coronary disease, thrombocytopenia, the rapid decrease in AT / B, C m-coronary steal.